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5:06
YouTube
Onkoview
The MAP-Kinase (MAPK) signalling pathway
The MAPK pathway is dysregulated in more than 50 % of all human tumors. The pathway starts with the activation of a receptor tyrosine kinase, which transmits the signal to a protein that catalyzes the exchange of the guanine nucleotide GDP for GTP associated with the membrane bound protein Ras. The activated GTP-bound form of Ras activates the ...
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