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Severe combined immunodeficiency
19:57
YouTubeDr. Andras Fazakas
Severe combined immunodeficiency
Severe combined immunodeficiency - A deadly combination of defects of T & B lymphocytes + Natural killer cells Its a primary immunodeficiency (inherited in the family) affecting T lymphoocytes, B lymphocytes and Natural killer cells in different combinations. These children die within one year without a bone marrow transplantation.There have ...
42.1K viewsSep 22, 2013
IL-2 Sturmovik Game
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IL-2 Sturmovik: Battle of Stalingrad
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SOLVED:Mutations in the IL2RG gene cause approximately 30 percent of severe combined immunodeficiency disorder (SCID) cases in humans. These mutations result in alterations to a protein component of cytokine receptors that are essential for proper development of the immune system. The I L 2 R G gene is composed of eight exons and contains upstream and downstream sequences that are necessary for proper transcription and translation. Below are some of the mutations observed. For each, explain its
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