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A new broad-spectrum antibiotic was administered by rapid intravenous injection to a 50-kg woman at a dose of 3 mg/kg. The apparent volume of distribution of this drug was equivalent to 5% of body weight. The elimination half-life for this drug is 2 hours.a. If 90% of the unchanged drug was recovered in the urine, what is the renal excretion rate constant?b. Which is more important for the elimination of the drug, renal excretion or biotransformation? Why?

A new broad-spectrum antibiotic was administered by rapid intrave…

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