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13:10
YouTube
Dr Ekram Desouky
MTHFR Mutations C677T / Tetrahydrofolate and the folate cycle
The MTHFR enzyme is an essential enzyme in the folate cycle. It directs folate species either to DNA synthesis or to homocysteine remethylation to methionine. MTHFR irreversibly reduces 5,10-methylenetetrahydrofolate (substrate) to 5-methyltetrahydrofolate. A common SNP in MTHFR is at base pair 677 (a change from a Cytosine to Thymine, C T ...
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