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SOLVED: If a native protein (folded protein) is denatured by theaddition of hydrochloric acid (HCl), would this changethe isoelectric point pI of the protein? If so, would the pIincrease or decrease upon denaturation? I know the isoelectricpoint is when the protein has a net charge of 0 but how would itchange if the protein is denatured by HCl?
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