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2:29
YouTube
FAST
Video Explanation of Angelman Syndrome presented by FAST
Angelman syndrome is caused by the loss in function of a single gene, UBE3A, on Chromosome 15 which is vital to how the brain controls speech, movement and learning. Only our mother's copy of UBE3A is expressed or active. The copy inherited from our father is silenced by a mechanism called the antisense transcript. In individuals with Angelman ...
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