Gene variation in TAS2R38 was associated with food intake and preference, and obesity risk. The genetic variation is involved with consumption of fruits, sweets and fat, it was shown in a research that non-tasters had higher intake of these food products that might lead to obesity.

The most studied gene in this family is TAS2R38, which encodes a receptor that mediates the capability to taste the bitter compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) [17].

Mar 8, 2025 · Gene target information for TAS2R38 - taste 2 receptor member 38 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

May 3, 2016 · The ability to taste phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) is a polymorphic trait mediated by the TAS2R38 bitter taste receptor gene.

Today we know that the ability to taste PTC (or not) is conveyed by a single gene that codes for a taste receptor on the tongue. The PTC gene, TAS2R38, was discovered in 2003.

Dec 25, 2024 · TAS2R38 (Taste 2 Receptor Member 38) is a Protein Coding gene. Diseases associated with TAS2R38 include Thiourea Tasting and Dental Caries. Among its related pathways are GPCR downstream signalling and Sensory perception of taste.

The human TAS2R38 gene encodes a bitter taste receptor that regulates the bitterness perception and differentiation of ingested nutritional/poisonous compounds in the oral cavity and gastrointestinal tract.

Dec 2, 2019 · The gene codifying for TAS2R38 receptor is characterized by three non-synonymous coding single nucleotide polymorphisms (SNPs) which result in two common variants of the TAS2R38 protein: the ...

Dec 20, 2023 · The Tas2r38 gene, also known as the “taste receptor 2 member 38”, is a gene that plays a crucial role in the sensation of bitter taste. It is primarily expressed in taste buds on the tongue and is responsible for detecting specific bitter compounds in our food and beverages.

Sep 5, 2017 · Polymorphisms in bitter taste receptor gene TAS2R38 alter the ability to sense the intensity of bitterness of phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP). Genetic variation in sensitivity towards PTC and PROP may affect food preferences and susceptibility to certain diseases.