In the meanwhile, we also analyzed the expression of JNK and p-JNK, which also play a vital role in the process of apoptosis. DSS significantly induced strong phosphorylation (activation) of JNK, however, the increased phosphorylation of JNK was suppressed by OCOP (50 mg/kg, 100 mg/kg). Discussion:

Western analysis of ERK, p-ERK and myogenic markers MyHC, MEF2C in siRNA-transfected myoblasts treated with 2μM PD0325901 or DMSO.

4 days ago · One hour after incubation in RPMI with 10% FCS, MAPK p38 inhibitor SB 203580, MEK 1 inhibitor PD 98059, JNK Inhibitor II SP600125 (Merck Chemicals Ltd, Nottingham, UK), NF-kB inhibitor BAY-11-7082 (Cayman, Ann Arbor, MI, USA), and lauroyl-γ-D-glutamyl-meso-diaminopimelic acid (C12-iE-DAP, Invivogen, Sweden) were administered for the indicated ...

Rabbit monoclonal anti-p-JNK(Thr183/Tyr185) antibody. Cell Signaling Technology. Cat#4668; RRID:AB_823588. 1:2000. Rabbit monoclonal anti-P38 antibody . Cell Signaling Technology. Cat#8690; RRID:AB_10999090. 1:1000. Rabbit monoclonal anti-p-P38 antibody. Cell Signaling Technology. Cat#4511;

Under NRICM-1 stimulation, THP-1 showed increased E-coli phagocytosis with p-JNK involvement. NRICM-01 stimulated THP-1 gain-in function were preserved when co-incubating serum derived from RA and SLE patients.

Figure S2. The effects of EEPS on intracellular Ca2+ accumulation in RAW 264.7 induced by LPS. The cells were treated with positive control dexamethasone (Dexa) 50 µM and EEPS (25, 50 ,100 µg/mL) for 2 h and then LPS 1 µg/mL was treated and incubated for 18 h.

JNK 9258S/Cell Signaling. p-JNK 9255S/Cell Signaling. P38 9212S/Cell Signaling. P-P38 9211S/Cell Signaling. P-P65 93H1/Cell Signaling. P65 8242S/Cell Signaling ...

The BskDN gene inserted into the Drosophila female chromosome suppressed endogenous JNK in female but not male flies. The activity of PucLacZ was monitored by red fluorescent antibody to β-galactosidase.

Supplementary Table 1. Primers used in this study. Target. Direction

The plasma levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were determined using a commercial kit (Nanjing Jiancheng Bioengineering Institute, Nanjing, China).