ZC3H18 Gene - GeneCards | ZCH18 Protein | ZCH18 Antibody
2024年12月25日 · ZC3H18 (Zinc Finger CCCH-Type Containing 18) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include RNA binding. An important …
ZC3H18 specifically binds and activates the - Nature
2019年10月11日 · We show that ZC3H18 is a DNA-binding protein that interacts with an E2F site in the BRCA1 promoter where it facilitates recruitment of E2F4 to an adjacent E2F site to …
ZC3H18 的双重激动和拮抗作用提供了不同核 RNA 衰变途径的共 …
我们进一步证明 ZFC3H1 和 ZC3H18 的类似富含酸性的短线性基序竞争共同的 ARS2 表位。 因此，在促进 NEXT 功能的同时，ZC3H18 拮抗 PAXT 活性。 我们认为，RNA 衰变复合物的这种 …
Characterizing ZC3H18, a Multi-domain Protein at the Interface of …
The ZC3H18 protein binds the cap-binding complex (CBC), universally present on capped RNAs, while also associating with the nuclear exosome targeting (NEXT) complex, linking to RNA …
Dual agonistic and antagonistic roles of ZC3H18 provide for co ...
2023年11月28日 · Here, mutational analysis of the core PAXT component ZFC3H1 uncovers a separate branch of the PAXT pathway, which targets short adenylated RNAs and relies on a …
ZC3H18 zinc finger CCCH-type containing 18 [ (human)]
Gene ID: 124245, updated on 9-Feb-2025. Enables mRNA cap binding complex binding activity and protein-macromolecule adaptor activity. Involved in RNA destabilization. Located in …
(PDF) Characterizing ZC3H18, a Multi-domain Protein at
2018年1月2日 · The ZC3H18 protein binds the cap-binding complex (CBC), universally present on capped RNAs, while also associating with the nuclear exosome targeting (NEXT) complex, …
ZC3H18 zinc finger CCCH-type containing 18 [ Homo sapiens …
2024年12月10日 · Title: ZC3H18 specifically binds and activates the BRCA1 promoter to facilitate homologous recombination in ovarian cancer. examination of ZC3H18 function, by genome …
The ZC3H18 protein is involved in RNA decay mediated by the CBC-NEXT complex. Winczura et al. identify a phosphorylation-dependent interaction of ZC3H18 with histones, and they find …
ZC3H18 specifically binds and activates the BRCA1 promoter to ...
2019年10月11日 · Reduced BRCA1 expression causes homologous recombination (HR) repair defects in high-grade serous ovarian cancers (HGSOCs). Here, we demonstrate that BRCA1 …