
Vesicular Glutamate Transporter 2 - an overview - ScienceDirect
The highly homologous protein VGLUT2, also initially characterized as a phosphate transporter and named differentiation-associated Na +-dependent inorganic phosphate transporter (DNPi), …
VGLUT2 Is a Determinant of Dopamine Neuron Resilience in a …
Jun 2, 2021 · Here we show that the subpopulation of midbrain dopaminergic neurons that express the vesicular glutamate transporter 2 (VGLUT2) are more resilient to rotenone …
Molecular, Structural, Functional, and Pharmacological Sites …
May 30, 2020 · VGLUT1 and VGLUT2 are expressed in distinct and complementary subsets of neurons in the CNS that display differences in release probability [36, 39]. VGLUT1 is the most …
Vesicular glutamate transporters are H - Nature
May 11, 2023 · In the mammalian central nervous systems, three vesicular glutamate transporters (VGLUT1, VGLUT2 and VGLUT3) are responsible for filling the synaptic vesicles of excitatory …
VGLUT2 Functions as a Differential Marker for Hippocampal …
Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for …
VGLUT substrates and inhibitors: A computational viewpoint
In this review, a new homology model for VGLUT2 based on DgoT has been developed and used to conduct docking experiments to identify and differentiate residues and binding orientations …
VGLUT2-expressing neurons in the vestibular nuclear complex …
May 8, 2020 · Vesicular glutamate transporter-2 (VGLUT2)-expressing neurons in the VNC have a crucial role in vestibular system-related thermoregulation. Our experiments first...
Ion transport and regulation in a synaptic vesicle glutamate ...
May 22, 2020 · We report the cryo–electron microscopy structure of rat VGLUT2 at 3.8-angstrom resolution and propose structure-based mechanisms for substrate recognition and allosteric …
Vesicular glutamate transporter VGLUT2 expression levels …
Nov 15, 2006 · Three transporters (VGLUT1-VGLUT3) are expressed in the mammalian CNS, with partial overlapping expression patterns, and VGLUT2 is the most abundantly expressed …
Differential Expression of VGLUT2 in Mouse Mesopontine …
Using a genetic fate-mapping strategy we found that most cholinergic neurons in the mouse mesopontine tegmentum express VGLUT2 at some point during development, including the …
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