Glutamate transporters are a family of neurotransmitter transporter proteins that move glutamate – the principal excitatory neurotransmitter – across a membrane. The family of glutamate …

Here we report that the vesicular-glutamate transporter 2 (VGLUT2) functions as a specific marker gene for subicular burst-firing neurons, and demonstrate that VGLUT2-Cre mice allow for …

2021年6月2日 · Here we show that the subpopulation of midbrain dopaminergic neurons that express the vesicular glutamate transporter 2 (VGLUT2) are more resilient to rotenone …

The highly homologous protein VGLUT2, also initially characterized as a phosphate transporter and named differentiation-associated Na +-dependent inorganic phosphate transporter (DNPi), …

2006年11月15日 · Three transporters (VGLUT1-VGLUT3) are expressed in the mammalian CNS, with partial overlapping expression patterns, and VGLUT2 is the most abundantly expressed …

2020年5月30日 · VGLUT1 and VGLUT2 are expressed in distinct and complementary subsets of neurons in the CNS that display differences in release probability [36, 39]. VGLUT1 is the most …

2020年5月8日 · Vesicular glutamate transporter-2 (VGLUT2)-expressing neurons in the VNC have a crucial role in vestibular system-related thermoregulation. Our experiments first...

2006年11月15日 · We show that targeted deletion of VGLUT2 in mice causes perinatal lethality and a 95% reduction in evoked glutamatergic responses in thalamic neurons, although …

2023年5月11日 · In the mammalian central nervous systems, three vesicular glutamate transporters (VGLUT1, VGLUT2 and VGLUT3) are responsible for filling the synaptic vesicles …

We report that conditional knockout (cKO) of the Slc17a6 gene encoding VGLUT2 from the great majority of nociceptors profoundly decreased VGLUT2 mRNA and protein in these neurons, …