Vesicular glutamate transporter 1 - Wikipedia
The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially …
VGLUT1 functions as a glutamate/proton exchanger with chloride …
Dec 22, 2017 · Here, we show by live-cell imaging with pH- and chloride-sensitive fluorescent probes in cultured hippocampal neurons of wild-type and VGLUT1-deficient mice that in SVs …
Vesicular glutamate transporters are H - Nature
May 11, 2023 · In summary, we provide evidence that VGLUT1 functions as H + -glutamate exchanger that is partially or fully uncoupled by other anions. Synaptic vesicles accumulate …
Research progress on the role of type I vesicular glutamate …
Mar 4, 2020 · VGLUT1 transport glutamate (Glu) mechanism diagram. VGLUT1 use proton electrochemical gradient generated by vascular ATPase to carry the glutamata anion (Glu) into …
Molecular, Structural, Functional, and Pharmacological Sites …
May 30, 2020 · Three subtypes of vesicular glutamate transporters (VGLUT1–3) have been identified that package glutamate into vesicles [34, 35, 36, 37, 38, 39, 40, 41, 42] reviewed in …
From glutamate co-release to vesicular synergy: vesicular …
Mar 18, 2011 · Vesicular glutamate transporter 1 (Vglut1) mRNA is found mostly in the cerebral cortex and hippocampus, and Vglut2 mRNA is found mostly in subcortical structures, including …
Protein Interactions of the Vesicular Glutamate Transporter VGLUT1
Exocytotic release of glutamate depends upon loading of the neurotransmitter into synaptic vesicles by vesicular glutamate transporters, VGLUTs. The major isoforms, VGLUT1 and 2, …
VGLUT1 mRNA and protein expression in the visual system of …
Dec 1, 2011 · Vesicular glutamate transporter 1 (VGLUT1) is widely distributed in the central nervous system of most mammalian and nonmammalian species, and regulates the uptake of …
Vesicular glutamate transporter 1 (VGLUT1)-mediated …
Mar 15, 2018 · Remarkably, VGLUT1 knockdown alleviated the rapid antidepressant-like actions of scopolamine and the effects of scopolamine on membrane GluA1-mediated BDNF, VGF …
VGLUT1: Its Impact on Neurotransmission and Brain Health
Feb 12, 2025 · VGLUT1, a vesicular glutamate transporter, is vital for neurotransmitter release and synaptic communication. Its role in packaging glutamate into synaptic vesicles directly …