
UVRAG Gene - GeneCards | UVRAG Protein | UVRAG Antibody
2024年12月25日 · UVRAG (UV Radiation Resistance Associated) is a Protein Coding gene. Diseases associated with UVRAG include Xeroderma Pigmentosum Group C and …
UVRAG - Wikipedia
UV radiation resistance-associated gene protein is a protein that in humans is encoded by the UVRAG gene. [5] [6] This gene complements the ultraviolet sensitivity of xeroderma …
UVRAG in autophagy, inflammation, and cancer - PubMed
UVRAG is one of the key players of autophagy, but its role in vivo remained puzzling. Our recent study utilized a mouse model with inducible expression of a cancer-derived frameshift (FS) …
Ubiquitination of UVRAG by SMURF1 promotes autophagosome ... - PubMed
UVRAG (UV radiation resistance associated) is an important regulator of mammalian macroautophagy/autophagy by interacting with BECN1, PIK3C3, and RUBCN. …
UVRAG UV radiation resistance associated [ (human)]
UVRAG is a regulator of CRL4 (DDB2)-mediated nucleotide excision repair and its expression levels may influence melanoma predisposition. Under-expression of UVRAG is associated …
UVRAG: At the crossroad of autophagy and genomic stability
UVRAG is a promoter of the autophagy pathway, and its deficiency may fuel the development of cancers. Intriguingly, our recent study has demonstrated that this protein also mediates the …
崔逸仙课题组发现了新的内质网自噬调控分子-武汉大学医学研究院
2023年11月6日 · 该研究发现,在哺乳动物细胞中,抗紫外线辐射相关基因UVRAG能有效增强内质网自噬起始点(ER-phagy sites, ERPHS)组装,促进内质网自噬发生。...
抗紫外线辐射相关(UVRAG)基因 | MCE - MCE-生物活性 ...
该基因补充了着色性干皮病 C 组细胞的紫外线敏感性,并编码具有 C2 结构域的蛋白质。 该蛋白激活 Beclin1-PI (3) KC3 复合物,促进自噬并抑制人结肠癌细胞的增殖和致瘤性。 涉及该基因的 …
UVRAG: orchestrating the initiation of reticulophagy - PubMed
Our study identified the multifunctional protein UVRAG (UV radiation resistance associated gene) as a novel regulator of reticulophagy. UVRAG interacts with sheet and tubular reticulophagy …
UVRAG 在自噬、炎症和癌症中的作用。,Autophagy - X-MOL
uvrag 是自噬的关键参与者之一,但其在体内的作用仍然令人困惑。 我们最近的研究利用了 UVRAG 中可诱导表达癌源移码 (FS) 突变的小鼠模型,该突变显性负抑制野生型 UVRAG,导 …