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TSPAN32 suppresses chronic myeloid leukemia pathogenesis and ...
2023年3月1日 · Tspan32 overexpression significantly prevented BCR-ABL induced leukemia progression in a murine model and impaired leukemia stem cell (LSC) proliferation.
TSPAN32 - Wikipedia
Tetraspanin-32 is a protein that in humans is encoded by the TSPAN32 gene. [5] [6] [7]
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四跨膜蛋白 32（TSPAN32）基因 | MCE - MCE-生物活性分子大师
关于 tspan32 Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:2,302,013-2,318,204 (from NCBI) This gene has 17 transcripts (splice variants), 102 orthologues and 32 …
Comprehensive Analysis of TSPAN32 Regulatory Networks and
2025年1月11日 · In this study, we performed a comprehensive analysis of the expression patterns and regulatory roles of TSPAN32. Notably, TSPAN32 is highly expressed in immune cells, …
Comprehensive Analysis of TSPAN32 Regulatory Networks and …
Tetraspanin 32 (TSPAN32), a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of chromosome …
Tspan protein family: focusing on the occurrence, progression, and ...
2024年4月22日 · However, Tspan32 stands as a notable exception to the overall pro-tumorigenic role of Tspans. Its overexpression effectively impedes leukemia progression and impairs the …
Comprehensive Analysis of TSPAN32 Regulatory Networks and …
2025年1月11日 · Tetraspanin 32 (TSPAN32), encoded by the TSPAN32 gene, located on human chromosome 11p15, is a bona fide member of the tetraspanin superfamily, although it differs …
<br>TSPAN32 通过稳定 PTEN 抑制慢性粒细胞白血病 …
我们在此报告， tspan32是费城 (ph + ) 白血病发病机制的关键节点因子。我们发现tspan32表达被 bcr-abl 抑制，并且伊马替尼治疗后异位 tspan32 表达抑制 ph +细胞系的增殖。 tspan32过表达可显着阻止 bcr-abl 在小鼠模型中诱导的白血病 …
Modulation of Tetraspanin 32 (TSPAN32) Expression in …
The present study focuses on the characterization of TSPAN32 in T cell responses and provides the first proof of concept for a possible role of TSPAN32 in the immune dysregulation observed in MS, defining this molecule as a …