
TREM1 - Wikipedia
Triggering receptor expressed on myeloid cells 1 (TREM1) is an immunoglobulin (Ig) superfamily transmembrane protein that, in humans, is encoded by the TREM1 gene.
The biology of TREM receptors - Nature Reviews Immunology
Feb 7, 2023 · Triggering receptors expressed on myeloid cells (TREMs) are a family of cell-surface receptors expressed broadly on myeloid cells. The first TREM identified, TREM1, was …
TREM1 Gene - GeneCards | TREM1 Protein | TREM1 Antibody
Dec 25, 2024 · TREM1 (Triggering Receptor Expressed On Myeloid Cells 1) is a Protein Coding gene. Diseases associated with TREM1 include Maxillary Sinusitis and Pneumonia. Among its …
The biology of TREM receptors - PMC
Triggering receptors expressed on myeloid cells (TREMs) are a family of cell-surface receptors expressed broadly on myeloid cells. The first TREM identified, TREM1, was characterized as …
The properties of TREM1 and its emerging role in pain-related …
TREM1 signaling pathway. TREM1, a member of the immunoglobulin superfamily, lacks any signaling motif in its intracytoplasmic domain due to its specific structural characteristics; …
TREM-1: intracellular signaling pathways and interaction with
TREM-1 is an important signaling receptor expressed on neutrophils and monocytes that plays an important role in systemic infections. Here, we review the intracellular signaling pathways that …
TREM1: Activation, signaling, cancer and therapy - PubMed
Triggering receptor expressed on myeloid cells 1 (TREM1) is a cell surface receptor expressed on neutrophils, monocytes and some tissue macrophages, where it functions as an …
TREM-1 and TREM-2 as therapeutic targets: clinical challenges …
Triggering receptor expressed on myeloid cells 1 (TREM-1) plays a pivotal role in human health and disease (1 – 6). Despite promising preclinical data and safety in humans, the first clinical …
TREM1 disrupts myeloid bioenergetics and cognitive function in …
Mar 27, 2024 · In vitro, Trem1 -deficient microglia are resistant to amyloid-β 42 oligomer-induced bioenergetic changes, suggesting that amyloid-β 42 oligomer stimulation disrupts homeostatic …
Peripheral TREM1 responses to brain and intestinal immunogens ... - Nature
Jul 1, 2019 · Here we demonstrate that peripheral CD11b + CD45 + myeloid cells magnify stroke injury via activation of triggering receptor expressed on myeloid cells 1 (TREM1), an amplifier …