
Tumor necrosis factor - Wikipedia
Tumor necrosis factor (TNF), formerly known as TNF-α, is a chemical messenger produced by the immune system that induces inflammation. [5] . TNF is produced primarily by activated macrophages, and induces inflammation by binding to its receptors on other cells. [6] .
TNF Gene - GeneCards | TNFA Protein | TNFA Antibody
2024年12月25日 · This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR.
The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune ...
Tumor necrosis factor alpha (TNF-α) was initially recognized as a factor that causes the necrosis of tumors, but it has been recently identified to have additional important functions as a pathological component of autoimmune diseases. TNF-α binds to two different receptors, which initiate signal transduction pathways.
TNF Pharmaceuticals, Inc. (TNFA) Stock Price, News, Quote ...
Find the latest TNF Pharmaceuticals, Inc. (TNFA) stock quote, history, news and other vital information to help you with your stock trading and investing.
TNF-α/NF-κB/Snail pathway in cancer cell migration and ...
2010年1月19日 · Understanding the mechanisms underlying inflammation-mediated metastasis will reveal new therapeutic targets for cancer prevention and treatment. Tumour necrosis factor (TNF)- α is a key...
TNF alpha and the TNF receptor superfamily: structure ...
2000年8月1日 · Tumour Necrosis Factor alpha (TNF alpha), is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and is responsible for a diverse range of signalling events within cells, leading to necrosis or apoptosis. The protein is also important for resistance to infection and cancers.
Tumor Necrosis Factor Alpha - an overview - ScienceDirect
Tumor Necrosis Factor Alpha (TNF-α) is a cytokine that acts as an arbitrator of the local tissue environment following injury, and is involved in bone tissue regeneration. It can initiate apoptosis and regulate cell survival and proliferation.