2023年7月5日 · Transient receptor potential (TRP) channels, which were first discovered in 1969, 1 they are multimodal ion channels that act as sensors of chemically toxic and physical...

Transient receptor potential vanilloid subtype 3 (TRPV3) is an ion channel with a sensory function that is most abundantly expressed in keratinocytes and peripheral neurons.

One major group of cell membrane-associated Ca 2+ -channels are formed by the Transient receptor potential (TRP) family proteins that can respond to various extracellular cues, including biochemical compounds, pH, heat, osmolarity and physical stimuli, to trigger activation of specific intracellular cascades through subtle changes in ion influx ...

2019年6月24日 · Transient receptor potential ion channel subfamily V (TRPV) is one of the largest and most diverse subfamilies, including TRPV1–TRPV6 involved in the regulation of a variety of...

Among these ion channels are the members of the transient receptor potential (TRP) family. To date, the most studied member of the TRP family is the TRPV1 receptor.

Cation-selective transient receptor potential (TRP) channels play important roles in numerous physiological processes and are known as polymodal sensors that integrate a wide range of physical and chemical stimuli in cellular signaling 1.

In signal transduction of metazoan cells, transient receptor potential (TRP) ion channels have been identified to respond to diverse external and internal stimuli, among them osmotic and mechanical stimuli. This chapter summarizes findings on the TRPV subfamily, both its vertebrate and invertebrate members, with a focus on TRPV4.

2024年12月25日 · TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1) is a Protein Coding gene. Diseases associated with TRPV1 include Cystinosis, Nephropathic and Pulpitis. Among its related pathways are Ion channel transport and CREB Pathway.

Transient receptor potential vanilloid type 2, TRPV2, is a calcium-permeable cation channel belonging to the TRPV channel family. This channel is activated by heat (>52 °C), various ligands, and mechanical stresses.

2023年1月12日 · As a Ca 2+ -permeable nonselective cation channel, TRPV3 can recognize thermal stimulation (31-39 °C), and it plays an important regulatory role in temperature perception, pain transduction, skin physiology, inflammation, cancer and other diseases.