tert-Butyldiphenylsilyl - Wikipedia
tert-Butyldiphenylsilyl, also known as TBDPS, is a protecting group for alcohols. Its formula is C 16 H 19 Si-. [1] The tert -butyldiphenylsilyl group was first suggested as a protecting group by …
Introduction of tert -butyldiphenylsilyl (TBDPS) group
Oct 6, 2021 · The tert -butyldiphenylsilyl (TBDPS) protection has been commonly used for primary hydroxyl groups in carbohydrate chemistry (1). A primary hydroxyl group can be preferentially …
tert -Butyldiphenylsilyl ethers - Organic Chemistry Portal
Various tert -butyldimethylsilyl (TBDMS) ethers as well as tert -butyldiphenylsilyl (TBDPS) ethers can be easily deprotected by employing a catalytic amount of acetyl chloride in dry MeOH in …
Protecting Groups For Alcohols - Master Organic Chemistry
Jun 17, 2015 · Tetrahydropyranyl (THP) ethers are also useful protecting groups for alcohols. What Would Be A Chemical Equivalent of “Painter’s Tape”? 1. When Alcohols Get In the Way. …
Silyl groups are typically deprotected with a source of fluoride ion. The Si–F bond stength is about 30 kcal/mol stronger than the Si–O bond. Monosilylation of symmetrical diols is possible, and …
tert -Butyldimethylsilyl ethers - Organic Chemistry Portal
TBDMS ethers can be cleaved selectively in the presence of isopropylidine, Bn, Ac, Bz, THP, and TBDPS groups using tetrabutylammonium tribromide in methanol. This method is high …
A mild method for rapid tert-butyldiphenylsilylation of primary …
Jun 11, 1993 · Reaction of the alcohol and tBDPSCl in DMF with AgN03, NH4NO3, or NH4C104 provides good yields of the corresponding silyl ethers.
「保护羧基」TBDPS、TBS、THP - ChemicalBook
Feb 26, 2021 · TBDPS保护基对许多与TBDMS保护基不相容的试剂显出比TBDMS基团更好的稳定性。 TBDMS基团在酸性条件下不易迁移。 碱性稳定条件：1、K2CO3 /CH3OH；2、9M氨水 …
Deprotection of Silyl Ethers - Gelest
The clean deprotection or desilylation of a silyl-protected functional group is essential to its utility.
叔丁基二苯基氯硅烷 | 58479-61-1 - ChemicalBook
叔丁基二苯基氯硅烷又称硅烷保护剂，其作用是硅烷基取代化合物中的活泼氢 (如羟基、羧基和氨基中的氢)，生成稳定的中间体；然后，该中间体的其他基团在进行某些反应；反应结束后， …