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    Wikipedia
    https://en.wikipedia.org/wiki/TAS2R38
    TAS2R38 - Wikipedia
    代号TAS2R38; PTC; T2R61
    扩展标识遗传学：607751 鼠基因：2681306 同源基因：47976 GeneCards: TAS2R38 Gene
    Signal transduction

    As with all TAS2R proteins, TAS2R38 utilizes the G-protein gustducin as its primary method of signal transduction. Both the α- and βγ-subunits are crucial to the transmission of the taste signal. See: taste receptor… 展开

    Ligands

    To date, a total of 23 distinct ligands have been identified for the T2R38 bitter taste receptor. These ligands have been extensively cataloged and documented in the comprehensive database known as BitterDB. … 展开

    Tissue distribution

    Taste GPCRs are expressed not only in the oral cavity but also in extra-oral tissues. Bitter taste receptors that are expressed in extra-oral tissues fill a variety of functional physiological roles. TAS2R38 is expressed in many tissues, … 展开

    Clinical significance

    Differential ability to taste the bitter compound phenylthiocarbamide (PTC) was discovered more than 80 years ago. Since then, PTC tasting ability has been mapped to chromosome 7q and, several years later, was shown to b… 展开

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