The incorporation of stem cells, such as embryonic stem cells, neural stem cells, bone marrow mesenchymal stem cells, adipose stem cells, skin-derived precursor stem cells and induced pluripotent stem cells has enhanced the therapeutic effects of tissue-engineered nerve grafts.

Researchers in the Mayo Clinic Center for Regenerative Biotherapeutics are developing numerous approaches to attenuate specific immune cell types in central nervous system (CNS) inflammation and applying strategies to a variety of diseases, including inflammation developing in the course of stem cell transplant, gene therapy or factor-driven ...

In recent years, cell transplantation has been proposed as a method of improving peripheral nerve regeneration. SCs activated in response to nerve injury, as previously described play a key role in Wallerian degeneration and formation of bands of Büngner.

2024年4月11日 · Stem cell therapy for neuropathy involves using stem cells to regenerate damaged nerve cells and improve nerve function in peripheral neuropathy. Research suggests stem cells can differentiate into nerve cells, promoting nerve regeneration and potentially relieving neuropathic symptoms.

Stem cells have the potential to increase the number of SCs and prolong their ability to support regeneration. They may also have the ability to rescue and replenish populations of chromatolytic and apoptotic neurons following axotomy.

Scientists have isolated a variety of stem cells from different organs and tissues in the human body and demonstrated that these cells were efficacious in regenerative medicine. The use of these cells provides a non-surgical method for the treatment of …

2020年2月27日 · The incorporation of stem cells as seed cells into the biomaterial-based scaffolds increases the effectiveness of tissue-engineered nerve grafts and largely boosts the regenerative process.