Dec 25, 2024 · SRRM1 (Serine And Arginine Repetitive Matrix 1) is a Protein Coding gene. Diseases associated with SRRM1 include Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 7. Among its related pathways are Processing of Capped Intron-Containing Pre-mRNA and RHOBTB GTPase Cycle.

Serine/arginine repetitive matrix protein 1 is a protein that in humans is encoded by the SRRM1 gene. [5] [6]

SRRM1 affected the level of key molecules p-JAK2, JAK2, p-STAT3, and STAT3 in the JAK/STAT pathway. Conclusion: SRRM1 played a significant role in the proliferation, migration, invasion and apoptosis of HCC, and promoted cancer by regulating the JAK/STAT signaling pathway.

Feb 8, 2025 · serine/arginine repetitive matrix protein 1, SR-related nuclear matrix protein of 160 kDa, Ser/Arg-related nuclear matrix protein. We discovered that two factors, SRRM1 and SF3B1, affect not only cis-SAGe chimeras, but also other types of …

Ubiquitous expression in ovary (RPKM 22.6), prostate (RPKM 22.3) and 25 other tissues. 启用 RNA 结合活性。 预计通过剪接体参与 mRNA 剪接。 位于核斑点。 催化步骤 2 剪接体的一部分。 妊娠糖尿病的生物标志物。 [由基因组资源联盟提供，2022 年 4 月] Enables RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nuclear speck. Part of catalytic step 2 spliceosome.

探讨丝氨酸/精氨酸重复基质1（SRRM1）对肝细胞癌（HCC）的调控作用及其潜在通路。 通过蛋白质印迹和免疫组织化学测试组织中的SRRM1水平。 分别通过 EdU、流式细胞术、伤口愈合试验和 Transwell 测试细胞增殖、凋亡、迁移和侵袭。 通过GSEA富集分析和GeneMANIA蛋白-蛋白相互作用（PPI）网络探索了SRRM1的潜在机制。 免疫共沉淀法用于检测 PPI。 通过蛋白质印迹测试 Bcl-2、Bax、Cleaved caspase 3、E-cadherin、N-cadherin、波形蛋白、p-JAK2、JAK2 …

May 8, 2024 · The SRRM1 entry clone from DNASU was modified using a Q5 site directed mutagenesis kit (New England Biolabs) to delete the predicted region responsible for nuclear speckle localization as ...

Feb 8, 2025 · Positional proteomics analysis identifies the cleavage of human serine/arginine repetitive matrix 1 (SRRM1) at amino acid residues 123-124 by the HIV-1 protease: PubMed

Feb 8, 2025 · Orthologous to human SRRM1 (serine and arginine repetitive matrix 1). [provided by Alliance of Genome Resources, Feb 2025] serine/arginine repetitive matrix protein 1, Ser/Arg-related nuclear matrix protein, plenty-of-prolines-101. Predicted to enable DNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome.

Chromosome 1: 24,958,207-24,999,758 forward strand. This gene has 24 transcripts (splice variants). Sorry, the page request "/Homo_sapiens/Component/Gene/Summary/gene_summary?db=core;g=ENSG00000133226;r=1:24958207-24999758;time=1742220963896.896" failed to load.