
SOX3 Gene - GeneCards | SOX3 Protein | SOX3 Antibody
2024年12月25日 · SOX3 (SRY-Box Transcription Factor 3) is a Protein Coding gene. Diseases associated with SOX3 include Intellectual Developmental Disorder, X-Linked, With Panhypopituitarism and Panhypopituitarism, X-Linked. Among its related pathways are Signaling by WNT and ERK Signaling.
SOX3 - an overview | ScienceDirect Topics
SOX3 is a protein that belongs to the B group of the large Sox proteins. It is involved in neural ectoderm specification and acts as a mesodermal suppressor in the ectoderm by negatively regulating Nodal signaling.
SOX3 SRY-box transcription factor 3 [ (human)] - National Center …
Transcription factor SOX3 upregulated pro-apoptotic genes expression in human breast cancer. A SOX3 duplication and lumbosacral spina bifida in three generations. LINC00662 Promotes Proliferation and Invasion and Inhibits Apoptosis of Glioma Cells Through miR-483-3p/SOX3 Axis.
The Sox Family of Transcription Factors: Versatile Regulators of …
Upon differentiation into NPCs, Sox2 collaborates with Sox3 to relocate from pluripotent to neural specific gene enhancers. These enhancers are either active in NPCs and hence carry the H3K4me3 mark or are inactive and carry bivalent marks.
SOX3 - an overview | ScienceDirect Topics
Sox3 is a single-exon gene located on the X chromosome in all mammals. It is expressed throughout the central nervous system, but particularly in the ventral diencephalon and infundibulum, and is necessary for correct morphogenesis of Rathke's pouch.
SOX Transcription Factors as Important Regulators of Neuronal …
Some SOX TFs suspend neural progenitors in proliferative, stem-like state and prevent their differentiation. SOX proteins function as pioneer factors that occupy silenced target genes and keep them in a poised state for activation at subsequent stages of differentiation.
SOX3 promotes generation of committed spermatogonia in
2020年4月21日 · Using a panel of spermatogonial cell marker genes, we demonstrate that Sox3 is expressed within the committed progenitor fraction of the undifferentiated spermatogonial pool. Additionally, we use...
Sox3 Is Required for Gonadal Function, but Not Sex …
We conclude that Sox3 is not required for gonadal determination but is important for normal oocyte development and male testis differentiation and gametogenesis. Sox3 is a single-exon gene located on the X chromosome (38) and expressed in the brain and gonads.
Entry - *313430 - SRY-BOX 3; SOX3 - OMIM
Stevanovic et al. (1993) cloned and characterized SOX3. A reverse transcription coupled with PCR (RT-PCR) was used to amplify SRY-related transcripts expressed during embryogenesis in human fetal spinal cord.
SOX3 SRY-box transcription factor 3 - NIH Genetic Testing …
2023年12月25日 · Serum proteome profiling reveals SOX3 as a candidate prognostic marker for gastric cancer. Xq27.1 Duplication Encompassing SOX3: Variable Phenotype and Smallest Duplication Associated with Hypopituitarism to Date - A Large Case Series of Unrelated Patients and a Literature Review.
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