
Small cell carcinoma of ovary, hypercalcemic type
2023年7月26日 · E. SMARCA4 / BRG1. SCCOHT is molecularly defined by inactivating SMARCA4 mutations, which are associated with SMARCA4 / BRG1 nuclear loss of …
Pathology Outlines - Undifferentiated carcinoma
2021年4月27日 · SMARCA4 (BRG1), SMARCA2 (BRM) or SMARCB1 (INI1) aberrant loss (Dis Esophagus 2009;22:1, Am J Surg Pathol 2021;45:414) Sample pathology report Esophagus, …
Pathology Outlines - Uterus
O-Z: perivascular epithelioid cell tumor (PEComa) POLE ultramutated endometrial carcinoma progestin therapy related changes serous carcinoma SMARCA4 deficient uterine sarcoma …
Pathology Outlines - Adenocarcinoma overview
2023年2月27日 · SMARCA4 loss of function: 5% (Ann Diagn Pathol 2017;26:47) Molecular / cytogenetics images. Contributed by ...
Pathology Outlines - Germ cell tumors
SMARCA4 deficient undifferentiated tumor: Focal rhabdoid morphology Loss of SMARCA4 (BRG1) Large B cell lymphoma / primary mediastinal large B cell lymphoma: Discohesive …
Pathology Outlines - Squamous cell carcinoma
2023年8月8日 · Squamous cell carcinoma is a malignant tumor arising from epithelial cells with squamous differentiation demonstrated either immunohistochemically or morphologically, with …
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2024年2月6日 · 4 genetically defined groups and 4 histologically defined groups (Nature 2017;547:311) Genetically defined: (a) WNT (for wingless integration site) activated, (b) SHH …
Pathology Outlines - Malignant
2024年6月13日 · NUT carcinoma and SMARCA4 deficient thoracic tumors: Features favoring NUT carcinoma and SMARCA4 deficient thoracic tumors: high N:C ratio, focal abrupt …
Pathology Outlines - Stains & CD markers
Soft tissue: AE1 / AE3 ALK1 caldesmon CAMTA1 CCNB3 (pending) CD31 CD34 CD99 CDK4 D2-40 DDIT3 (pending) desmin DOG1 DUX4 EBER EMA ERG factor XIIIa FLI1 FOSB …
Pathology Outlines - INI1 / SMARCB1
2022年6月1日 · SMARCB1 (switch / sucrose non fermentable [SWI / SNF] related, matrix associated, actin dependent regulator of chromatin subfamily B member 1) is located on …