2024年12月25日 · STK11 (Serine/Threonine Kinase 11) is a Protein Coding gene. Diseases associated with STK11 include Peutz-Jeghers Syndrome and Testicular Germ Cell Tumor. …

2022年8月12日 · STK11, also sometimes known as LKB1, is a gene that tells your body to make an enzyme called serine/threonine kinase 11. People who have a change, or mutation, in their …

The STK11 gene (also called LKB1) provides instructions for making an enzyme called serine/threonine kinase 11. This enzyme is a tumor suppressor, which means that it helps …

What is the STK11 mutation? Errors in the STK11 gene are one type of lung cancer biomarker. Mutations in the STK11 gene (also called LKB1) inactivate the STK11 protein. This leads to …

2024年9月6日 · An inherited STK11 (Peutz-Jeghers Syndrome) mutation may affect your options for cancer prevention, detection and treatment. FORCE is here to guide you.

STK11 overexpression prevents glucocorticoid-induced osteoporosis via activating the AMPK/SIRT1/PGC1alpha axis. Glutaminase inhibition impairs CD8 T cell activation in STK11 …

2024年12月12日 · What is my cancer risk if I have an STK11 mutation? If you have a mutation in the STK11 gene, this means you have a condition called Peutz-Jeghers syndrome (PJS). …

We present three patients with STK11‐mutated tumors and discuss the proposed mechanisms by which germline and somatic alterations in STK11 promote carcinogenesis, potential …

The STK11 mutation defines a special subtype of lung adenocarcinoma (LUAD) patients, and emerging evidences suggested that STK11 alterations may be prognostic and/or predictive of …

STK11 is a tumor suppressor gene that encodes for an enzyme called serine/threonine kinase 11 which is involved in AMPK pathway and regulates cell polarity. You might find these chapters …