
Retinoid X receptor beta - Wikipedia
Retinoid X receptor beta (RXR-beta), also known as NR2B2 (nuclear receptor subfamily 2, group B, member 2) is a nuclear receptor that in humans is encoded by the RXRB gene. [5] [6]This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms heterodimers with the retinoic …
RXRB Gene - GeneCards | RXRB Protein | RXRB Antibody
2024年12月25日 · RXRB (Retinoid X Receptor Beta) is a Protein Coding gene. Diseases associated with RXRB include Granulomatosis With Polyangiitis and Vasculitis. Among its related pathways are NR1H2 and NR1H3-mediated signaling and Gene expression (Transcription).
RXRB retinoid X receptor beta [ (human)] - National Center for ...
Gene ID: 6257, updated on 8-Feb-2025. This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA).
Rxrb retinoid X receptor beta [ (house mouse)] - National Center …
2025年2月8日 · Enables chromatin DNA binding activity and transcription cis-regulatory region binding activity. Involved in cellular response to retinoic acid. Acts upstream of or within several processes, including cardiac muscle tissue development; maternal placenta development; and positive regulation of transcription by RNA polymerase II.
RXRB retinoid X receptor beta [ Homo sapiens (human) ]
2021年3月2日 · RXR interaction is necessary for NPM-RAR-mediated myeloid maturation arrest. Title: Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade. A fatty acid-binding protein 7/RXRbeta pathway enhances …
Nuclear RXRα and RXRβ receptors exert distinct and
2019年3月1日 · RXRA promotes cell cycle arrest, dopaminergic phenotype and neuritogenesis. RXRA restrains ERK1/2 overactivation. RXRB inhibits neuritogenesis. Retinoic acid (RA) promotes differentiation in multiple neurogenic cell types by promoting gene reprogramming through retinoid receptors and also by inducing cytosolic signaling events.
RXRB | Cancer Genetics Web
Network rewiring clearly characterizes the dynamic regulatory systems of distinct disease states. This study is the first to associate an RXRB-causal network with increased risks of nodal metastasis, tumor relapse, distant metastases and poor survival for oral cancer.
Entry - *180246 - RETINOID X RECEPTOR, BETA; RXRB - OMIM
2000年8月31日 · HGNC Approved Gene Symbol: RXRB. Cytogenetic location: 6p21.32 Genomic coordinates (GRCh38) : 6:33,193,588-33,200,853 (from NCBI) The retinoic acid receptors, alpha (RARA; 180240), beta (RARB; 180220), and gamma (RARG; 180190), require coregulators to bind effectively to response elements and target genes.
Rxrb MGI Mouse Gene Detail - MGI:98215 - retinoid X receptor beta
View mouse Rxrb Chr17:34250786-34257373 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
Function of retinoic acid receptors during embryonic development
Homologous recombination in embryonic stem cells has been used to generate germline null mutations of the RAR- and RXR-coding genes in the mouse.