Dec 25, 2024 · RRM2B (Ribonucleotide Reductase Regulatory TP53 Inducible Subunit M2B) is a Protein Coding gene. Diseases associated with RRM2B include Mitochondrial Dna Depletion …

Ribonucleotide-diphosphate reductase subunit M2 B is an enzyme that in humans is encoded by the RRM2B gene. [5] [6] [7] [8] The gene encoding the RRM2B protein is located on …

The RRM2B gene provides instructions for making one piece, called the p53 inducible small subunit (p53R2), of a protein called ribonucleotide reductase (RNR). Learn about this gene …

RRM2B-related mitochondrial DNA depletion syndrome, encephalomyopathic form with renal tubulopathy (RRM2B-MDS) is a severe condition that begins in infancy and affects multiple …

Nov 8, 2012 · RRM2B is the DNA damage-inducible small subunit of ribonucleotide reductase, the rate-limiting enzyme in de novo deoxyribonucleoside triphosphate synthesis. Although RRM2B …

Feb 9, 2025 · Identification of two novel RRM2B variants associated with autosomal recessive progressive external ophthalmoplegia in a family with pseudodominant inheritance pattern. …

该基因的突变与常染色体隐性遗传线粒体 DNA 耗竭综合征、常染色体显性遗传进行性外眼肌麻痹 5 和线粒体神经胃肠脑病有关。 已经描述了选择性剪接的转录变体。 [RefSeq 提供，2010 年 2 …

Our study is the first to report the critical role of RRM2B in mitochondrial homeostasis and the inflammation signaling pathway in a p53-independent manner. Furthermore, our study …

The RRM2B gene encodes the small subunit of p53 (191170)-inducible ribonucleotide reductase, a heterotetrameric enzyme responsible for de novo conversion of ribonucleoside diphosphates …

这个基因编码p53诱导型核糖核苷酸还原酶的小亚基。 这个异四聚酶催化核糖核苷酸二磷酸转化为脱氧核糖核苷酸二磷酸。 这个反应的产物对DNA合成是必需的。 这个基因的突变与常染色体 …