RANTES (regulated upon activation, normal T cell expressed and secreted [also known as CCL5]) is a model chemokine of relevance to a myriad of diseases. Regulation of RANTES expression is complex. In fibroblasts and monocytes, rel proteins alone …

Treatment with Met-RANTES, a functional inhibitor of CCL5, at the second phase of CCL5 production reduced immunopathology, suggesting that CCL5 receptors play a central role in driving inflammation in RSV lung disease.

Dec 24, 2024 · CCL5 (C-C Motif Chemokine Ligand 5) is a Protein Coding gene. Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway.

Jun 9, 2021 · CCL5，CC类趋化因子配体5，也称为调节激活正常T细胞表达分泌因子（RANTES），是一种能使白细胞作定向移动的小分子分泌蛋白。 CCL5来源广泛，如NK、T、巨噬细胞、滑膜成纤维细胞，炎症反应中的CD8+ T细胞、上皮细胞、成纤维细胞和血小板，病毒感染后的细胞，以及某些肿瘤细胞。 CD40、IL-15等不同刺激物激活NF-kB会诱导CCL5的产生。 …

CCL5 or RANTES (regulated on activation, normal T-cell expressed and secreted) is a CC chemokine that is stored in the alpha granules of platelets and that can be rapidly released after platelet activation.

Nov 29, 2016 · CCL5/RANTES, and its receptor CCR5 are known to contribute to neuronal function as well as to metabolic disorders such as type 2 diabetes mellitus, obesity, atherosclerosis and metabolic...

CCL5/CCR5 axis promotes VEGF production by attracting endothelial progenitor cells (EPCs). The CCL5-overexpressing-osteosarcoma makes EPCs migrate to abnormal sites.

Explore the role of CCL5 (RANTES), a crucial chemokine involved in immune responses, inflammation, and various diseases. Learn about its function, regulation, clinical significance, and potential therapeutic applications.

Oct 1, 2007 · CC Chemokine Ligand-5 (CCL5/RANTES) and CC Chemokine Ligand-18 (CCL18/PARC) Are Specific Markers of Refractory Unstable Angina Pectoris and Are Transiently Raised During Severe Ischemic Symptoms

RANTES (regulated upon activation, normal T cell expressed and secreted [also known as CCL5]) is a model chemokine of relevance to a myriad of diseases. Regulation of RANTES expression is...