The seminal discovery of ribonuclease P (RNase P) and its catalytic RNA by Sidney Altman has not only revolutionized our understanding of life, but also opened new fields for scientific …

Ribonuclease P (RNase P) is an ancient and essential endonuclease that catalyses the cleavage of the 5′ leader sequence from precursor tRNAs (pre-tRNAs). The enzyme is one of only two …

RNase P is an endo-ribonuclease required for processing precursor tRNA into mature tRNA. RNase P is a highly conserved ribonucleoprotein composed of (i) an RNA ribozyme that …

Oct 1, 2006 · Ribonuclease P (RNase P) is a ubiquitous endonuclease that catalyses the maturation of the 5′ end of transfer RNA (tRNA).

RNase P is responsible for generating the mature 5′-end of tRNAs by a single endonucleolytic cleavage of their precursors. It is an essential, ubiquitous enzyme present in all cells and …

Feb 12, 2024 · RNase P is recruited to DNA DSBs and represses H3.3 recruitment to actively transcribed genes. RPP21 and RPP29 are recruited to DNA DSBs by binding to PAR moieties, …

Ribonuclease P (RNase P) is an essential endonuclease responsible for catalyzing 5’ end maturation in precursor transfer RNAs. Since its discovery in the 1970s, RNase P enzymes …

Jun 18, 2022 · Ribonuclease P (RNase P) enzymes are responsible for the 5′ processing of tRNA precursors. In addition to the well-characterised ribozyme-based RNase P enzymes, an …

We outline early works on human RNase P as a tRNA processing enzyme and comment on its expanding nonconventional functions in molecular networks of transcription, chromatin …

May 9, 2024 · Ribonuclease P (RNase P) was first described in the 1970's as an endoribonuclease acting in the maturation of precursor transfer RNAs (tRNAs). More recent …