
RNase II regulates RNase PH and is essential for cell survival …
RNase II is the most active exoribonuclease in Escherichia coli cell extracts. Yet, its removal appears to have no deleterious effect on growing cells. Here, we show that RNase II is …
2IX0: RNase II - RCSB PDB
Ribonuclease II (RNase II) is a major exoribonuclease that intervenes in all of these fundamental processes; it can act independently or as a component of the exosome, an essential RNA …
Unravelling the dynamics of RNA degradation by ribonuclease II
2006年9月7日 · RNase II is a ubiquitous exoribonuclease that processively hydrolyses RNA in the 3′ to 5′ direction, releasing 5′ monophosphates 1. The enzyme binds RNA and in the presence …
The Escherichia coli major exoribonuclease RNase II is a …
RNase II, the 644 amino-acid product of the rnb gene, is the major hydrolytic exoribonuclease in E. coli. RNase II acts processively from the 3′ end of single-stranded RNA substrates and …
Here we review recent progresses in the understanding of the degradation mechanism of RNase II, based on mutational analysis and their characterization regarding catalysis and RNA affinity.
Action of RNase II and Polynucleotide Phosphorylase against …
RNase II can also be stimulated by polyadenylation in vitro, but to a more limited extent . In order to resolve the paradoxical properties of RNase II and PNPase, we compared their abilities to …
The importance of proteins of the RNase II/RNB-family in …
RNase II from Escherichia coli is the prototype of this family, which also includes bacterial RNase R and eukaryotic Rrp44/Dis3 proteins. These proteins present a similar modular organization …
New Insights into the Mechanism of RNA Degradation by Ribonuclease II
RNase II is a key exoribonuclease involved in the maturation, turnover, and quality control of RNA. RNase II homologues are components of the exosome, a complex of exoribonucleases. …
RNase II binds to RNase E and modulates its endoribonucleolytic ...
2020年4月17日 · To our knowledge, Anabaena RNase II is an unusual ribonuclease that interacts with the catalytic domain of RNase E, and it may represent a new type of RNA degradosome …
Swapping the domains of exoribonucleases RNase II and RNase R …
RNase II and RNase R are the two E. coli exoribonucleases that belong to the RNase II super family of enzymes. They degrade RNA hydrolytically in the 3' to 5' direction in a processive …