Thermo Scientific RNase A, DNase and protease-free is an endoribonuclease that specifically degrades single-stranded RNA at C and U residues. It cleaves the phosphodiester bond between the 5'-ribose of a nucleotide and the phosphate group attached to the 3'-ribose of an adjacent pyrimidine nucleotide.

RNase A, or Ribonuclease A, is an endonuclease that catalyzes the degradation of RNA. This enzyme is primarily known for its ability to cleave single-stranded RNA, which is paramount in regulating RNA levels within cells.

RNase A catalyzes the transphosphorylation and degradation of RNA. It was the first protein identified to exhibit DNA melting functionality. This enzyme binds to several binding sites on single stranded (ss) RNA polynucleotide chain before degrading it.

Bovine pancreatic ribonuclease, also often referred to as bovine pancreatic ribonuclease A or simply RNase A, is a pancreatic ribonuclease enzyme that cleaves single-stranded RNA. Bovine pancreatic ribonuclease is one of the classic model systems of protein science. [1] .

RNase A (bovine pancreatic ribonuclease) is the founding member an extensive family of divergent proteins that share specific elements of sequence homology, a unique disulfide-bonded tertiary structure, and the ability to hydrolyze polymeric RNA.

RNase A is an endoribonuclease with functions in RNA metabolism and regulation of gene expression. RNase A has been found to play important roles in diseases such as autoimmune diseases, renal insufficiencies and pancreas disorders.

Bovine pancreatic ribonuclease A (RNase A) catalyzes the cleavage of P–O 5′ bonds in RNA. Structural analyses had suggested that the active-site lysine residue (K41) may interact preferentially with the transition state for covalent bond cleavage, thus facilitating catalysis.

RNase A is an endoribonuclease that cleaves single-stranded RNA, specifically on the 3′ side of pyrimidine (cytosine and uracil) nucleotides (Py/pN). You might find these chapters and articles relevant to this topic.

2019年8月15日 · RNase A refers to an enzyme which promotes the breakdown of RNA into oligonucleotides and smaller molecules while RNase H refers to an endoribonuclease which specifically hydrolyzes the phosphodiester bonds of RNA, which is hybridized to DNA.

Ribonuclease A (RNase A) is an endoribonuclease that cleaves single-stranded RNA at the 3´ end of pyrimidine residues, forming oligoribonucleotides having 3´-terminal pyrimidine-3´-phosphates. Pyrimidine-3´-monophosphates are also released by RNase A cleavage of adjacent pyrimidine nucleotides.