RNA polymerase II - Wikipedia
The carboxy-terminal domain of RNA polymerase II typically consists of up to 52 repeats of the sequence Tyr-Ser-Pro-Thr-Ser-Pro-Ser. [32] The domain stretches from the core of the …
RNA聚合酶Ⅱ - 维基百科，自由的百科全书
釀酒酵母的RNA聚合酶Ⅱ包含有12个亚基 [4] 。. 早期的研究表明至少有两种RNAP：一种在核仁中合成rRNA，另一种在核质中合成其他RNA，核一部分但在核仁外 [5] 。 在1969年，科学实验 …
RNA polymerase II holoenzyme - Wikipedia
RNAPII can exist in two forms: RNAPII0, with a highly phosphorylated CTD, and RNAPIIA, with a nonphosphorylated CTD. [16] Phosphorylation occurs principally on Ser2 and Ser5 of the …
RNA聚合酶Ⅱ - 百度百科
RNA聚合酶Ⅱ（英语：RNA polymerase II，亦被称为RNAPⅡ或PolⅡ）是一种存在于真核生物细胞中的酶。它催化脱氧核糖核酸转录，合成mRNA及大多数hnRNA和微RNA的前体。
RNA Polymerase II - an overview | ScienceDirect Topics
RNA polymerase II (Pol II) is a multi-subunit enzyme involved in transcribing all protein-coding genes in eukaryotes. 1,2 The largest subunit of Pol II (RPB1) contains a series of seven …
Dynamic control of RNA-DNA hybrid formation orchestrates DNA2 ...
Feb 6, 2025 · Our results suggest that the dynamic regulation of RNA-DNA hybrid formation at stalled forks by RNAPII and DDX39A precisely governs the timing of DNA2 activation, …
RNAPII-dependent ATM signaling at collisions with replication forks
Aug 24, 2023 · We show the ATPase WRNIP1 associates with RNAPII and limits ATM activation during unperturbed cell cycle. WRNIP1 binding to elongating RNAPII requires catalytic activity …
【Cell论文拆解】DNA损伤停滞处的RNAPII的泛素化 促进转录耦合 …
通过防止RNA聚合酶II (RNA polymerase II，RNAPII)在DNA损伤处的长期停滞，TC-NER确保了转录的迅速恢复和避免细胞凋亡。TC-NER是由DNA损伤处拉长的RNAPII分子(RNAPII …
RNA polymerase II is required for spatial chromatin reorganization ...
Oct 22, 2021 · Here, we tested the role of RNA polymerase II (RNAPII) in this transition using a cell line that allows its auxin-mediated degradation. In situ Hi-C showed that RNAPII is …
The Long Road to Understanding RNAPII Transcription Initiation and ...
Jun 20, 2021 · This review summarizes nearly five decades of work on transcription initiation by describing the sequential recruitment of diverse molecular players including the GTFs, the …