2024年12月25日 · PTAFR (Platelet Activating Factor Receptor) is a Protein Coding gene. Diseases associated with PTAFR include Anaerobic Pneumonia and Acute Pancreatitis. Among its related pathways are GPCR downstream signalling and Class A/1 (Rhodopsin-like receptors).

The platelet-activating factor receptor (PAF-R) is a G-protein coupled receptor which binds platelet-activating factor. [5][6] It is encoded in the human by the PTAFR gene. The PAF receptor shows structural characteristics of the rhodopsin (MIM 180380) gene family and binds platelet-activating factor (PAF).

PTAFR is an important regulatory factor for NET formation in AS, influencing the progression and prognosis of atherosclerosis. Targeting PTAFR may provide new therapeutic strategies for AS. The online version contains supplementary material available at 10.1186/s40246-024-00708-3.

PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes.

Number of protein-coding transcripts from the gene as defined by Ensembl. A summary of the overall protein expression profile across the analyzed normal tissues based on knowledge-based annotation, presented in the Tissue resource. "Estimation of protein expression could not be performed. View primary data."

2024年11月2日 · PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes.

2025年1月4日 · PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes.

2024年8月16日 · FUNCTION: Receptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth- muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol- calcium second messenger system. SUBUNIT: Interacts with ARRB1.

2005年2月18日 · Platelet-activating factor receptor is a G protein-coupled receptor that binds platelet-activating factor (PAF), a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes (summary...

PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes.