
PRKCH Gene - GeneCards | PKHUO Protein | PKHUO Antibody
2024年12月25日 · PRKCH (Protein Kinase C Eta) is a Protein Coding gene. Diseases associated with PRKCH include Stroke, Ischemic and Cortical Dysplasia, Complex, With Other Brain Malformations 13. Among its related pathways are Prolactin Signaling and ADORA2B mediated anti-inflammatory cytokines production.
PRKCH regulates hematopoietic stem cell function and predicts …
2017年9月1日 · PRKCH is highly expressed in human and mouse hematopoietic stem cells and in acute myeloid leukemia (AML) stem cells. PRKCH deficiency compromises hematopoietic stem cell function. Elevated PRKCH expression correlates with RUNX1 and TP53 mutations in AML patients and predicts poor overall survival.
PRKCH protein kinase C eta [ (human)] - National Center for ...
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways.
PRKCH protein expression summary - The Human Protein Atlas
PRKCH is a prognostic marker in Kidney renal clear cell carcinoma Cancer specificity i Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, cancer enhanced, low cancer specificity and not detected.
PRKCH protein kinase C eta [ Homo sapiens (human) ]
2024年4月3日 · Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways.
Entry - *605437 - PROTEIN KINASE C, ETA; PRKCH - OMIM
2007年2月23日 · By screening a human keratinocyte cDNA library using PRKCA fragments as probes, Bacher et al. (1991) isolated a cDNA encoding PRKCH, which they called PKCL. The predicted PRKCH protein contains 680 amino acids and …
PRKCH protein kinase C eta - NIH Genetic Testing Registry (GTR)
2024年9月18日 · Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways.
Prkch (house mouse) | Gene Target - PubChem
2016年9月14日 · The protein encoded by the Prkch gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus.
Overexpression of PRKCH promotes tumorigenesis in patients …
PRKCH expression level is an independent prognostic factor in glioma patients, promoting poor prognosis and shorter survival in glioma patients. Furthermore, overexpression of PRKCH in glioma stem cells significantly increased stem cell properties and enhanced cell viability.
Prkch protein kinase C, eta [ (house mouse)] - National Center for ...
2025年2月19日 · Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways.
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