Dec 25, 2024 · PLAU (Plasminogen Activator, Urokinase) is a Protein Coding gene. Diseases associated with PLAU include Quebec Platelet Disorder and Alzheimer Disease, Familial, 1. …

Urokinase, also known as urokinase-type plasminogen activator (uPA), is a serine protease present in humans and other animals. The human urokinase protein was discovered, but not …

PLAU is a promising new candidate gene for late-onset Alzheimer's disease, with allele C (P141) being a recessive risk allele or allele T (L141) conferring protection. u-PA down-regulation by …

Jan 4, 2025 · Title: PLAU contributes to the development of cholangiocarcinoma via activating NF-κB signaling pathway. Involvement of matrix metalloproteinase 1 and urokinase-type …

Jan 4, 2025 · Clinical resource with information about PLAU, Alzheimer disease type 1, Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease., …

Plasminogen activator, urokinase (PLAU) is involved in cell migration, proliferation and tissue remodeling. PLAU upregulation is associated with an increase in aggressiveness, metastasis, …

Sep 14, 2016 · Gene target information for PLAU - plasminogen activator, urokinase (human). Find diseases associated with this biological target and compounds tested against it in …

The urokinase-type plasminogen activator(PLAU) and its receptor PLAUR participate in a series of cell physiological activities on the extracellular surface. Abnormal expression of PLAU and …

These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further …

Urinary plasminogen activator (uPA, PLAU; EC 3.4.21.73) converts plasminogen (173350) to plasmin. Urokinase has a molecular mass of about 54 kD and is composed of 2 disulfide …