2024年12月25日 · PTGS2 is the principal isozyme responsible for production of inflammatory prostaglandins. New generation PTGSs inhibitors strive to be selective for PTGS2, to avoid …

Herein, we review the main effects of this molecular pathway in a tissue-specific manner, with a special emphasis on beta cell mass protection/destruction and its potential role in the …

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are …

2024年5月22日 · Prostaglandin-endoperoxide synthase 2 (PTGS2, also called COX2) acts as an oncogenic driver in CRC. Here, we explored the upstream transcription factors (TFs) …

Background: The prostaglandin-endoperoxide synthase 2 [PTGS2, commonly known as cyclooxygenase-2 (COX-2)] is an enzyme induced by proinflammatory stimuli that is often …

Very important pharmacogene: PTGS2. This PharmGKB summary briefly discusses the PTGS2 gene and current understanding of its function, structure, regulation, and pharmacogenomic …

2023年8月6日 · The inducible Prostaglandin Endoperoxide Synthase 2/Cyclooxygenase 2 (PTGS2/COX2) plays an important role in pathologies associated with inflammatory signaling. …

2016年9月14日 · Gene target information for PTGS2 - prostaglandin-endoperoxide synthase 2 (human). Find diseases associated with this biological target and compounds tested against it …

2024年5月1日 · PTGS2 (encode COX2) is related to inflammatory pathway and immune cell infiltration. COX2 inhibitor celecoxib suppressed mast cell degranulation and allergic reactions. …

4 天之前 · PTGS2, a key enzyme in PGE2 synthesis, is considered one of the key factors regulating ferroptosis . The induction of disease by PTGS2 through mediating ferroptosis has …