PLGA, PLG, or poly(lactic-co-glycolic) acid (CAS: 26780-50-7) is a copolymer which is used in a host of Food and Drug Administration (FDA) approved therapeutic devices, owing to its biodegradability and biocompatibility. [1]

PLGA is biocompatible and biodegradable, exhibits a wide range of erosion times, has tunable mechanical properties and most importantly, is a FDA approved polymer.

Poly(lactic-co-glycolic) acid (PLGA) has attracted considerable interest as a base material for biomedical applications due to its: (i) biocompatibility; (ii) tailored biodegradation rate (depending on the molecular weight and copolymer ratio); ...

Poly-lactic-co-glycolic acid (PLGA) has been the most successful polymeric biomaterial for use in controlled drug delivery systems. There are several different chemical and physical properties of PLGA that impact the release behavior of drugs from ...

Jan 1, 2023 · Poly (lactic-co-glycolic acid) (PLGA) is a biodegradable polymer with a lot of potential in pharmaceutical nanotechnology and novel drug carrier systems due to its superior properties. PLGA is noted for its biocompatibility and biodegradability when hydrolytically degraded into nontoxic compounds, glycolic acid, and lactic acid via natural ...

Polylactic-co-glycolic acid (PLGA) is one of the extensively researched synthetic biodegradable polymers due to its favorable properties. It is also known as a 'Smart Polymer' due to its stimuli sensitive behavior.

Jul 20, 2012 · This review presents why PLGA has been chosen to design nanoparticles as drug delivery systems in various biomedical applications such as vaccination, cancer, inflammation and other diseases.

Feb 28, 2014 · This paper critically reviews the scientific challenge of manufacturing PLGA-based materials with suitable properties and shapes for specific biomedical applications, with special emphasis on bone tissue engineering.

聚乳酸-羟基乙酸共聚物（poly(lactic-co-glycolic acid)，PLGA）由两种单体——乳酸和羟基乙酸随机聚合而成，是一种可降解的功能高分子有机化合物，具有良好的生物相容性、无毒、良好的成囊和成膜的性能，被广泛应用于制药、医用工程材料和现代化工业领域。

Jun 29, 2021 · This article provides an overview of FDA's PLGA research program and highlights scientific accomplishments as well as regulatory outcomes that have resulted from successful research investigations.