Platelet-derived growth factor-BB (PDGF-BB):PDGF receptor-β (PDGFRβ) signalling in brain pericytes is critical to the development, maintenance and function of a healthy blood-brain …

PDGF is a dimeric glycoprotein consisting of two distinct, disulfide-linked peptide chains (A and B) found as a homodimer (PDGF-AA or PDGF-BB) or as a heterodimer (PDGF-AB). PDGF is …

Diliberto P.A., Gordon G.W., Yu C.L., Earp H.S., Herman B. Platelet-derived growth factor (PDGF) α receptor activation modulates the calcium mobilizing activity of the PDGF β receptor in …

2024年10月28日 · We herein validated PDGF-BB as a potential therapeutic and prognostic tool of ovarian cancer aggressiveness. Platelet derived growth factors (PDGFs) family includes …

PDGF-BB is a powerful promoter of cell proliferation and increases the expression of stem cell markers; inhibites collagen production and mineraliration but accelerates the maturation of …

2018年8月2日 · PDGF-BB, CC, and DD increased the FSS-induced decline in MMP-2 expression. These results indicate that MMP-2 is regulated by FSS and contributes to the FSS-induced …

Platelet-derived growth factor (PDGF) is a potent mitogen involved in cell proliferation and migration. PDGF-BB induces the proliferation and migration of PASMCs and has been …

BACKGROUND Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized …

2022年3月17日 · Platelet-derived growth factor-BB (PDGF-BB):PDGF receptor-β (PDGFRβ) signalling in brain pericytes is critical to the development, maintenance and function of a …

2024年12月18日 · Our findings reveal a novel anti-senescence role of PDGF in the IVD, demonstrating its ability to alleviate the senescent phenotype and protect against the …