
Characterisation of PDGF-BB:PDGFRβ signalling pathways in …
Platelet-derived growth factor-BB (PDGF-BB):PDGF receptor-β (PDGFRβ) signalling in brain pericytes is critical to the development, maintenance and function of a healthy blood-brain …
Platelet Derived Growth Factor BB - an overview - ScienceDirect
PDGF is a dimeric glycoprotein consisting of two distinct, disulfide-linked peptide chains (A and B) found as a homodimer (PDGF-AA or PDGF-BB) or as a heterodimer (PDGF-AB). PDGF is …
Role of platelet-derived growth factors in physiology and …
Diliberto P.A., Gordon G.W., Yu C.L., Earp H.S., Herman B. Platelet-derived growth factor (PDGF) α receptor activation modulates the calcium mobilizing activity of the PDGF β receptor in …
Platelet Derived Growth Factor BB: A “Must-have” Therapeutic …
2024年10月28日 · We herein validated PDGF-BB as a potential therapeutic and prognostic tool of ovarian cancer aggressiveness. Platelet derived growth factors (PDGFs) family includes …
Role of PDGF-BB in proliferation, differentiation and ... - PubMed
PDGF-BB is a powerful promoter of cell proliferation and increases the expression of stem cell markers; inhibites collagen production and mineraliration but accelerates the maturation of …
Platelet-Derived Growth Factor Receptor-α and β are Involved …
2018年8月2日 · PDGF-BB, CC, and DD increased the FSS-induced decline in MMP-2 expression. These results indicate that MMP-2 is regulated by FSS and contributes to the FSS-induced …
Role of platelet-derived growth factor-BB (PDGF-BB) in human ... - PubMed
Platelet-derived growth factor (PDGF) is a potent mitogen involved in cell proliferation and migration. PDGF-BB induces the proliferation and migration of PASMCs and has been …
PDGF-BB: Human Platelet Derived Growth Factor-BB
BACKGROUND Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized …
Characterisation of PDGF-BB:PDGFRβ signalling pathways in
2022年3月17日 · Platelet-derived growth factor-BB (PDGF-BB):PDGF receptor-β (PDGFRβ) signalling in brain pericytes is critical to the development, maintenance and function of a …
Protective effects of PDGF-AB/BB against cellular senescence in
2024年12月18日 · Our findings reveal a novel anti-senescence role of PDGF in the IVD, demonstrating its ability to alleviate the senescent phenotype and protect against the …
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