
【研究报告】CD7靶点:清君侧 - 健康界
Aug 22, 2022 · CD7 (T细胞抗原7,又称作GP40,TP41,LEU-9)是一种单链跨膜糖蛋白,40kDa,,包含240个氨基酸残基,属于免疫球蛋白超家族成员。 CD7通常表达于85%的外 …
Expression and function of CD7 molecule on human natural ... - PubMed
Jan 15, 1994 · CD7 on human NK cells was found to be a signal-transducing molecule with a rapid increase in cytoplasmic free calcium observed on binding of anti-CD7 mAb to the surface …
Elevated KIR expression and diminished intensity of CD7 on NK …
Aug 30, 2022 · In addition, CD7 median fluorescent intensity and CD2 + CD7 − frequencies were significantly lower in HIV patients. A distinct population of KIR3DL1/S1 cells was unexpectedly …
Heterogeneity of human bone marrow and blood natural killer …
Sep 2, 2019 · Recently, the definition of the NK cell-restricted progenitor population has been redefined as Lin − CD34 + CD38 + CD123 − CD45RA + CD7 + CD10 + CD127 − cells as a …
Functionally distinct subsets of human NK cells and monocyte/DC …
Nov 26, 2009 · Our data indicate that CD7 and CD56 coexpression discriminates NK cells from CD7(neg)CD56+ monocyte/DC-like cells, thereby improving our ability to study the intricacies …
CD7分子的基础及其免疫靶向治疗在血液系统恶性疾病中的研究进 …
CD7分子是人体免疫细胞膜上一类重要的表面标志物,在淋巴细胞发育成熟过程中发挥协同刺激分子受体的作用。 CD7分子作为血液系统恶性疾病的肿瘤细胞表面的异常标志物,在急性T淋巴 …
问:什么是CD7? - 知识科普—干细胞治疗新闻中心 - 细胞生物大会 …
答:cd7是一种跨膜糖蛋白,属于免疫球蛋白超家族。 在正常人体内主要分布于T细胞、NK细胞及其前体细胞表面。 CD7在白血病克隆细胞中异常表达,在正常髓系细胞上则不存在,这使 …
CD7在NK/T细胞淋巴瘤中的表达及与预后的相关性研究 - PMC
分析cd7在nk/t细胞淋巴瘤(nktcl)中的表达情况,并探讨其与生存及预后的相关性。 方法
结果112 例NKTCL 患者中CD7 阳性表达率为84.82%,其表达与性别、年龄 、原发部位无关。 对临床资料完整的72 例患者进行分析,结果表明,CD7 的表达与PINK 评分、肿 瘤转移、外周血EBV …
Functionally distinct subsets of human NK cells and monocyte/DC …
Functionally, only CD7 + NK cells secrete gamma interferon (IFNγ) and degranulate after interleukin-12 (IL-12) plus IL-18 or K562 target cell stimulation. Furthermore, using CD7 to …