2024年12月25日 · NFIA (Nuclear Factor I A) is a Protein Coding gene. Diseases associated with NFIA include Brain Malformations With Or Without Urinary Tract Defects and Bilateral Polymicrogyria. Among its related pathways are RNA Polymerase III Transcription Initiation and Gene expression (Transcription).

2025年2月10日 · The Netherlands Foreign Investment Agency (NFIA) assists businesses looking to invest in Holland. Discover the benefits and our services.

Nuclear factor I (NFI) proteins constitute a family of dimeric DNA-binding proteins with similar, and possibly identical, DNA-binding specificity. They function as cellular transcription factors and as replication factors for adenovirus DNA replication.

2019年2月25日 · NFIA-induced astrocytes promote synaptogenesis, exhibit neuroprotective properties, display calcium transients in response to appropriate stimuli and engraft in the adult mouse brain.

2017年8月14日 · Here, we identified nuclear factor I-A (NFIA) as a transcriptional regulator of brown fat by a genome-wide open chromatin analysis of murine brown and white fat followed by motif analysis of...

2024年11月29日 · 为了进一步理解星形胶质细胞在记忆提取中的具体作用，研究人员对NFIA基因进行了研究。 他们发现，学习事件激活的星形胶质细胞中NFIA蛋白的表达水平会升高。 阻断这些星形胶质细胞中的NFIA基因会抑制记忆的回忆，而且这种抑制具有一定的记忆特异性。 Kwon指出，当在学习事件期间剔除星形胶质细胞中活跃的NFIA基因时，小鼠无法回忆起与该学习事件相关的特定记忆，但可以回忆起其他记忆。 研究者认为，与学习相关的星形胶质细胞群可能是特定 …

2019年6月13日 · NFIA-related disorder comprises central nervous system abnormalities (most commonly abnormalities of the corpus callosum) with or without urinary tract defects, such as unilateral or bilateral vesicoureteral reflux and hydronephrosis.

Here we identify nuclear factor IA (NFIA) as a molecular switch inducing human glial competency. Transient expression of NFIA is sufficient to trigger glial competency of human pluripotent stem cell-derived neural stem cells within 5 days and to convert these cells into astrocytes in the presence of glial-promoting factors, as compared to 3-6 ...

2019年6月13日 · NFIA-related disorder comprises central nervous system abnormalities (most commonly abnormalities of the corpus callosum) with or without urinary tract defects, such as unilateral or bilateral vesicoureteral reflux and hydronephrosis. Additional features include macrocephaly, seizures, developmental delay and/or cognitive impairment ...

The Netherlands Foreign Investment Agency (NFIA) is an operational unit of the Dutch Ministry of Economic Affairs. NFIA helps and advises foreign companies on the establishment, rolling out, and expansion of their international activities in the Netherlands.