A time-dependent release of endogenous free DHA followed by NPD1 formation occurs, suggesting that a phospholipase A2 releases the mediator's precursor. When NPD1 is infused …

Protectin D1 also known as neuroprotectin D1 (when it acts in the nervous system) and abbreviated most commonly as PD1 or NPD1 is a member of the class of specialized …

我们前期研究表明,抗炎促修复脂质小分子（PRLMs）参与调控急慢性疼痛；而神经保护素D1（NPD1）是一种新型PRLM，具有强大的神经保护作用，但其受体未知，在化疗诱发神经 …

神经保护素D1(neuroprotectin D1，NPD1)是一种由视网膜色素上皮细胞合成产生的介质，来源于二十二碳六烯酸(docosahexaenoic acid，DHA)的氧化反应，能够抑制细胞因子诱导的促炎因 …

Protectin D1 is one of the specialised proresolving mediators. When produced in neural tissues, it is called neuroprotectin D1 It has a role as an anti-inflammatory agent, a neuroprotective …

Apr 5, 2006 · In oxidative stress‐challenged human RPE cells and rat brain undergoing ischemia‐reperfusion, 10,17S‐docosatriene (neuroprotectin D1, NPD1) synthesis evolves. In …

Jan 5, 2011 · Neuroprotectin D1 (NPD1) is a stereoselective mediator derived from the omega-3 essential fatty acid docosahexaenoic acid (DHA) with potent inflammatory resolving and …

Neuroprotectin D1 (NPD1), the first-identified stereoselective bioactive product of DHA, exerts neuroprotection in models of experimental stroke by down-regulating brain ischemia …

Apr 21, 2017 · Neuroprotectin D1 (NPD1), a docosahexaenoic acid (DHA)-derived lipid mediator, promotes cell survival under uncompensated oxidative stress (UOS). Our data demonstrate …

Apr 1, 2022 · Neuroprotectin D1 (NPD1), a potent lipid anti-inflammatory mediator, is made in the brain and other peripheral immune cells on demand and counteracts inflammation and cell …