NLRX1 or NLR family member X1, short for nucleotide-binding oligomerization domain, leucine rich repeat containing X1 is a protein that in humans is encoded by the NLRX1 gene. [5] [6] It …

The Nod-like receptor NLRX1 has many diverse, multifaceted roles in innate immune system signaling, and cellular localization plays a key role in determining NLRX1's function. Localized …

2008年1月16日 · Here we describe human NLRX1, a highly conserved nucleotide-binding domain (NBD)- and leucine-rich-repeat (LRR)-containing family member (known as NLR) that localizes …

2024年12月25日 · NLRX1 (NLR Family Member X1) is a Protein Coding gene. Diseases associated with NLRX1 include Long Qt Syndrome and Histiocytic Sarcoma . Among its …

2022年12月1日 · NLRX1 regulates systemic energy metabolism through its biological function in mitochondria, but the metabolic regulatory mechanism of NLRX1 is very complex and is …

NLRX1 is an underappreciated member of the NOD‐like receptor family. Functions in pathogen response are responsible for the regulation of multiple immune pathways. Emergence in …

NLRX1 is the first reported NLR that specifically controls ROS production. The human genome database shows the existence of NLRX1, an uncharacterized NLR on the 11q23.3 locus that …

2025年2月9日 · NLRX1 increases human retinal pigment epithelial autophagy and reduces H2O2-induced oxidative stress and inflammation by suppressing FUNDC1 phosphorylation and …

Recent evidence has suggested that NLRX1 controls mitophagy through the detection of a specific "danger signal", namely the defective import of proteins into mitochondria, or …

2008年1月31日 · Here we describe human NLRX1, a highly conserved nucleotide-binding domain (NBD)- and leucine-rich-repeat (LRR)-containing family member (known as NLR) that localizes …