
NFE2L2 Gene - GeneCards | NF2L2 Protein | NF2L2 Antibody
2024年12月25日 · NFE2L2 (NFE2 Like BZIP Transcription Factor 2) is a Protein Coding gene. Diseases associated with NFE2L2 include Immunodeficiency, Developmental Delay, And …
NFE2L2 Is a Potential Prognostic Biomarker and Is Correlated with ...
Our findings revealed the possible role of NFE2L2 across cancers, suggesting that NFE2L2 is a potential prognostic biomarker and is correlated with immune infiltration in many cancers, …
NFE2L2 and ferroptosis resistance in cancer therapy - PMC
NFE2-like basic leucine zipper transcription factor 2 (NFE2L2, also known as NRF2), is a key transcription factor in the cellular defense against oxidative stress, playing a crucial role in …
NFE2L2 NFE2 like bZIP transcription factor 2 [ (human)]
NFE2L2 modulates autophagy gene expression and suggests a new strategy to combat proteinopathies. Identify an Nrf2-mediated 17-gene signature, which reflects a cluster of gene …
Nuclear factor, erythroid 2-like 2-associated molecular ... - Nature
2015年11月24日 · Nuclear factor, erythroid 2-like 2 (NFE2L2), a transcription factor also known as NF-E2-related factor 2 (Nrf2), is a key cytoprotective gene that regulates critical antioxidant …
Activating de novo mutations in NFE2L2 encoding NRF2 cause a ...
2017年10月10日 · Somatic mutations of NFE2L2 leading to NRF2 accumulation promote cell survival and drug resistance in cancer cells. Here we show that the same mutations as inborn …
NFE2L2 - an overview | ScienceDirect Topics
NFE2L2 is a master regulator of antioxidant/detoxifying system. GABPA controls the transcription of many mitochondrial/metabolic genes. NFE2L2, GABPA and PGC-1alpha are implicated in …
Regulation and function of the NFE2 transcription factor in ...
The elimination of ROS is largely accomplished by induction of NFE2L2 (NRF2) targets and since NFE2 shows very similar binding specificity, it can compete with NFE2L2 for induction of …
NFE2L2 Is a Potential Prognostic Biomarker and Is Correlated with ...
2020年10月9日 · The present study revealed that NFE2L2 was abnormally expressed and significantly correlated with mismatch repair (MMR) gene mutation levels and DNA …
Investigating ferroptosis-related genes NFE2L2 in neutrophils for ...
6 天之前 · Ferroptosis gene NFE2L2 was identified as the final drug target of AS; it was upregulated in AS and downregulated in the control group by immunohistochemical …
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