Dec 25, 2024 · MT2A (Metallothionein 2A) is a Protein Coding gene. Diseases associated with MT2A include Scrapie and Immunodeficiency 48. Among its related pathways are Metal ion …

Metallothionein-2 is a metallothionein protein that in humans is encoded by the MT2A gene. [3] [4] The single-nucleotide polymorphism rs28366003 which substitutes guanine for adenine in …

与癌旁正常组织相比，crc患者肿瘤组织中金属硫蛋白2a（mt2a）表达下调，且与患者肿瘤m分期相关。mt2a过表达抑制crc细胞增殖和细胞内迁移，以及crc动物模型中的生长和转移。而 …

Aug 23, 2019 · Our results show that MT2A level could be used as a predictive biomarker of resistance to chemotherapy, and provide with preclinical rational for MT2A targeting as a …

Mammalian metallothionein-2A (MT2A) has received considerable attention in recent years due to its crucial pathophysiological role in anti-oxidant, anti-apoptosis, detoxification and anti …

mt2a、mt1e、mt1x被认为是食管癌潜在的治疗新靶点。 在本研究中，与敏感组相比，免疫耐受组MT2A、MT1E、MT1X表达下调，并与肿瘤组织中CD8+效应T细胞等多种免疫细胞的浸润有关。

MT2A Promotes Oxaliplatin Resistance in Colorectal Cancer Cells. Expression profiles of metallothionein-I/II and megalin/LRP-2 in uterine cervical squamous lesions. MT2A is an early …

金属硫蛋白-2 (metallothionein-2,MT-2)作用广泛,具有多种生物学功能。本文介绍了MT-2生物学特性、表达调控机制和蛋白相互作用等研究进展,以期对MT-2蛋白有更全面的认识,并基于某一特 …

金属硫蛋白 2A： 该基因是金属硫蛋白基因家族的成员。该基因家族编码的蛋白质分子量低，富含半胱氨酸，不含芳香族残基，可结合二价重金属离子，改变细胞内重金属的浓度。这些蛋白质 …

Sep 6, 2016 · 哺乳动物金属硫蛋白-2a（mt2a）由于其在抗氧化剂，抗细胞凋亡，排毒和抗炎中的关键病理生理作用，近年来受到了相当大的关注。 多年来，大多数评估MT2A效果的研究都集 …