Dec 25, 2024 · LSM7 (LSM7 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. Diseases associated with LSM7 include …

U6 snRNA-associated Sm-like protein LSm7 is a protein that in humans is encoded by the LSM7 gene. [5] [6] [7]

Jun 28, 2022 · The dynamic Lsm7 phase-separated condensates appear to work as seeding scaffolds, promoting Pab1 demixing and subsequent SG initiation, seemingly mediated by …

Nov 1, 2024 · In this study, LSM7 was prominently expressed in metastatic breast cancer tissues and was associated with poor prognosis in patients with BC. LSM7 was shown to enhance BC …

Nov 1, 2024 · Aims: The RNA-binding protein LSM7 is essential for RNA splicing, acting as a key component of the spliceosome complex; however, its specific role in breast cancer (BC) has …

Feb 8, 2025 · RNA-binding protein LSM7 facilitates breast cancer metastasis through mediating alternative splicing of CD44. LSm1-7 proteins colocalize with DCP1,DCP2 and Xrn1 in …

Feb 11, 2014 · Analysis by mass spectrometry confirmed the presence of all seven Lsm proteins. Despite rigorous trials, we were unable to crystallize the Lsm1-7 complex. To solve this …

Jan 9, 2025 · LSM7 encodes a subunit of the LSM complex, involved in pre-RNA maturation and mRNA degradation. Consequently, it has been suggested as a strong candidate disease …

Nov 17, 2013 · Here we report the crystal structures of the heptameric Lsm complex, both by itself and in complex with a 3′ fragment of U6 snRNA, at 2.8 Å resolution. Each of the seven Lsm …

Correlations of LSM1, LSM2, LSM3, LSM4, LSM7, and LSM14B expressions with immune infiltration profiles in breast cancer (from TCGA database). The figures show the each LSM …