Aug 28, 2024 · The findings indicated that the overexpression of miR-369-3p resulted in enhanced lung function, reduced pulmonary edema, inflammation, and permeability in LPS-induced ALI mice, while the...

In this study, lipopolysaccharide (LPS) was used to induce ALI mice, demonstrating the ecacy of tetramethylpyrazine (TMP) in ameliorating ALI.

Sep 29, 2020 · We demonstrated that the ectopic induction of miR-369-3p markedly reduced iNOS mRNA and protein as well as NO production. Moreover, we found that the upregulation of miR-369-3p decreased the...

Aug 28, 2024 · The results of our study demonstrate that TMP mitigates LPS-induced ALI through upregulation of miR-369-3p. Consequently, the findings of this study advocate for the clinical utilization of TMP in ALI treatment, with miR-369-3p emerging as a …

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(a) RT-qPCR and Western blotting assays showed the mRNA and protein levels of JAK2 in OA chondrocytes transfected with shNC, shMSC-AS1 and shMSC-AS1+ miR-369-3p inhibitor.