2024年12月25日 · LIN28B (Lin-28 Homolog B) is a Protein Coding gene. Diseases associated with LIN28B include Acrocephalopolysyndactyly Type Iii and Neuroblastoma . Among its …

We show that LIN28B influences RAN expression by promoting RAN Binding Protein 2 expression and by directly binding RAN mRNA. Further, we demonstrate a convergence of LIN28B and …

LIN28B is an RNA-binding protein that targets a broad range of microRNAs and modulates their maturation and activity. Under normal conditions, LIN28B is exclusively expressed in …

2018年8月31日 · LIN28B is an evolutionarily conserved RNA-binding protein that regulates mRNA translation and miRNA let-7 maturation in embryonic stem cells and developing tissues. …

2023年6月15日 · Here, we report the cryo-EM structures of the nucleosome containing human LIN28B DNA derived from the chromatin locus bound by OCT4 during cell reprogramming and …

2025年2月8日 · Title: LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression. A Multi-Omics Approach Reveals Enrichment in …

2025年1月5日 · Lin28B is a novel marker for predicting prognosis in patients with oral squamous cell carcinoma; Lin28B is an oncofetal circulating cancer stem cell-like marker associated with …

In this review, we summarize the main similarities and differences between Lin28A and Lin28B, their implications in different cellular processes, and their role in different types of cancer.

2023年4月10日 · LIN28B is an RNA-binding protein that targets a broad range of microRNAs and modulates their maturation and activity. Under normal conditions, LIN28B is exclusively …

2014年8月8日 · We report that LIN28B overexpression is sufficient to initiate hepatoblastoma and hepatocellular carcinoma in murine models. We also detected Lin28b overexpression in MYC …