L-selectin, also known as CD62L, is a cell adhesion molecule found on the cell surface of leukocytes, and the blastocyst. It is coded for in the human by the SELL gene. L-selectin …

2019年5月14日 · L-selectin (CD62L) is a type-I transmembrane glycoprotein and cell adhesion molecule that is expressed on most circulating leukocytes. Since its identification in 1983, L …

L-selectin is the smallest of the vascular selectins, expressed on all granulocytes and monocytes and on most lymphocytes, can be found in most leukocytes. P-selectin, the largest selectin, is …

2023年7月19日 · L-selectin. L-selectin is a 74 to 100 kDa glycoprotein involved in lymphocyte homing and adhesion to endothelial cells in peripheral lymph nodes.

L-selectin is a cell adhesion molecule consisting of a large, highly glycosylated, extracellular domain, a single spanning transmembrane domain and a small cytoplasmic tail. It is …

L-selectin is a key adhesion molecule that regulates both the migration of leukocytes at sites of inflammation and the recirculation of lymphocytes between blood and lymphoid tissues.

L-selectin (CD62L) is expressed on most leukocytes. Its most important function is in lymphocyte homing to secondary lymphatic organs [297], but it also has an accessory function in …

2019年5月13日 · L-selectin shedding is a classic readout for neutrophil activation and/or “priming” (i.e., partial activation), which is concordant with an upregulation in CD11b expression (αMβ2 …

The selectins are transmembrane, Ca2+-dependent lectins that mediate leucocyte rolling on vascular surfaces, the first adhesive step during inflammation and immune surveillance. …

L‐selectin is a cell adhesion molecule consisting of a large, highly glycosylated, extracellular domain, a single spanning transmembrane domain and a small cytoplasmic tail. It is …

L-Selectin is a member of the selectin family of adhesion molecules that is expressed on all types of leukocytes. It functions as a homing receptor in naive lymphocytes, directing them to the …

This review focuses on the ligands for L-selectin that are found on vascular endothelium, leukocytes, carcinoma cells, and at various extravascular sites. The discovery of selectins and …

L-selectin, which is found on leukocytes, was the first discovered, by virtue of an interesting phenomenon called lymphocyte homing, in which lymphocytes were removed from various …

2012年4月1日 · The leukocytic cell adhesion receptor l-selectin mediates the initial step of the adhesion cascade, the capture and rolling of leukocytes on endothelial cells. This event …

L-selectin is a calcium-dependent lectin-like receptor1,2 that is widely distributed on all leukocytes in the blood and belongs to the newly emerging selectin family of cell-cell adhesion proteins, …

L-selectin expression on peripheral blood leucocytes in patients with SSc. The frequency of L-selectin-expressing leucocytes from patients with SSc was assessed (Figs 2 and 3).Although …

These parts of the selectin molecules are responsible for their targeting to different compartments: P-selectin to secretory granules, E-selectin to the plasma membrane, and L-selectin to the tips …

2002年2月1日 · This article reviews recent advances in the knowledge of the role of L-selectin, an adhesion molecule that is expressed on the surface of circulating leucocytes, in animal and …

L-selectin controls the capacity for naïve T cells to migrate to the lymph nodes (LN), whereas P- and E-selectin capture activated T cells on activated inflamed endothelium to initiate their …

2021年2月8日 · L-selectin is a cell adhesion molecule abundantly expressed on circulating neutrophils. For over two decades, neutrophil L-selectin has been assigned the exclusive role …

2025年3月1日 · The selectin family (P-, E-, and L-selectin) has been implicated in the endothelial-mediated inflammation during IR, with P-selectin being involved in the initial interaction …

The leukocytic cell adhesion receptor L-selectin mediates the initial step of the adhesion cascade, the capture and rolling of leukocytes on endothelial cells. This event enables leukocytes to …