
KLRC2 - Wikipedia
NKG2-C type II integral membrane protein or NKG2C is a protein that in humans is encoded by the KLRC2 gene. [3] [4] It is also known as or cluster of differentiation 159c (CD159c).
KLRC2 Gene - GeneCards | NKG2C Protein | NKG2C Antibody
2024年12月25日 · KLRC2 (Killer Cell Lectin Like Receptor C2) is a Protein Coding gene. Diseases associated with KLRC2 include Human Cytomegalovirus Infection and Nk Cell Deficiency. Among its related pathways are DAP12 interactions and Innate Immune System.
Activating NKG2C Receptor: Functional Characteristics and Current ...
The CD94/NKG2C receptor is encoded by the 6 kpb length NKG2C gene, also referred as KLRC2, located within the NK complex on chromosome 12p12.3–13.2 (Fig. 1). It consists of six exons and five introns.
KLRC2 killer cell lectin like receptor C2 [ (human)]
The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain.
Identification of KLRC2 as a candidate marker for brain tumor ...
KLRC2, a transmembrane activating receptor in natural killer cells, was expressed more highly in glioma-initiating cells than in neural stem cell lines or normal adult brain tissue. The q-PCR analysis revealed that expression of KLRC2 was significantly higher in brain tumor-initiating cells compared to normal brain controls.
KLRC2 killer cell lectin like receptor C2 [ Homo sapiens (human) ]
2025年2月8日 · The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain.
Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E …
2021年1月26日 · NKG2C is an activating NK cell receptor encoded by the KLRC2 gene, which binds to HLA-E on infected cells leading to NK cell activation. Heterozygous or homozygous KLRC2 deletion (KLRC2del) may...
KLRC2 protein expression summary - The Human Protein Atlas
KLRC2 is a prognostic marker in Glioblastoma multiforme Cancer specificity i Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, cancer enhanced, low cancer specificity and not detected.
Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and ... - PubMed
2018年5月31日 · Using novel RNA-based flow cytometry, we identify for the first time true memory NKG2C+ NK cells in NHP by gene expression (KLRC2), and show that these cells have elevated frequencies and diversify their functional repertoire specifically in response to rhCMV and SIV infections.
NKG2C/KLRC2 tumor cell expression enhances …
KLRC2 overexpression induced the downregulation of M2 markers (CD206 and ARG) and the upregulation of iNOS, an M1-related gene (online supplemental figure 3E), suggesting a direct effect of tumor cells expressing NKG2C on the profile of the associated macrophages.