Keratinization is defined as cytoplasmic events that take place in keratinocytes that move through the different layers of the epidermis to finally differentiate into corneocytes. You might find these chapters and articles relevant to this topic.

Keratinization, also termed as cornification, is a process of cytodifferentiation which the keratinocytes undergo when proceeding from their post germinative state (stratum basale) to finally differentiated, hardened cell filled with protein, constituting a structurally and functionally distinct keratin containing surface layer such as stratum ...

2023年12月14日 · In pathology, keratinization describes squamous cells producing and accumulating large amounts of a protein called keratin. Microscopically, this makes the cells look pink when stained with a combination of dyes called hematoxylin and eosin (H&E) .

keratinization The formation of, or conversion into, keratin. This normally occurs to a limited degree in the outer layers of the skin, but is especially prominent when skin is exposed to constant localized pressure.

This review article discusses the classification, structure, functions, the stains used for the demonstration of keratin and associated pathology. The review describes the physiology of keratinization, pathology behind abnormal keratin formation and various keratin disorders. Keywords: Keratinization, disorder, marker. INTRODUCTION

Applying the new consensus nomenclature, this article summarizes, for all human keratins, their cell type and tissue distribution and their functional significance in relation to transgenic mouse models and human hereditary keratin diseases.

2019年1月17日 · Keratin filaments are heteropolymeric, formed from equal amounts of acidic type I and basic /neutral type 2 keratins. Humans have 54 keratin genes (Schweitzer et al. 2006). They have highly specific expression patterns, related to the epithelial type and stage of differentiation.