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Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, also known as KCNN4, is a human gene encoding the K Ca 3.1 protein. [5] The K Ca 3.1 protein is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium.

2024年12月25日 · KCNN4 (Potassium Calcium-Activated Channel Subfamily N Member 4) is a Protein Coding gene. Diseases associated with KCNN4 include Dehydrated Hereditary Stomatocytosis 2 and Dehydrated Hereditary Stomatocytosis 1 With Or Without Pseudohyperkalemia And/Or Perinatal Edema.

由该基因编码的蛋白质是潜在的异四聚体电压依赖性钾通道的一部分，该通道可被细胞内钙激活。 激活之后是膜超极化，这会促进钙内流。 编码的蛋白质可能是 T 淋巴细胞中主要的钙激活钾通道的一部分。 该基因与其他 KCNN 家族钾通道基因相似，但差异很大，可能被视为新亚家族的一部分。 [RefSeq 提供，2008 年 7 月] The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent Potassium Channel that is activated by intracellular …

Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 , also known as KCNN1 is a human gene encoding the KCa2.1 protein. [4]

KCNN (97.7 FM) is a country music formatted broadcast radio station licensed to Benson, Arizona, serving western Cochise County and eastern Pima County. [1] . KCNN is owned and operated by through licensee Redrock Media Group LLC. [5]

KCNN Global Capital (“KCNN”) is an investment holding company based in Penang, Malaysia. Our primary objective is to research and identify valuable investment opportunities within the global capital market. The company is spearheaded by four remarkable business magnates with track records of success across multiple fields.

KCNN4 is a diagnostic and prognostic biomarker that promotes papillary thyroid cancer progression. In KCNN4-related disease, the main symptoms were more severe anemia, hemolysis and iron overload, with no clear sign of red cell dehydration; therefore, this disorder would be better described as a 'Gardos channelopathy'.

人类SKCa3也称KCNN3或SK3，有研究报道位于 人类染色体 1q21包含有某些家族性精神分裂症一个重要的易感位点，SKCa3通道蛋白氨基末端包含有一个高度多态性的 多聚谷氨酸 重复序列（CAG）n。 不同人群相关研究发现，在精神分裂症患者中较长的重复序列显著地过度表达，并发现其与精神分裂症阴性症状高度相关。 然而也有家系研究报道认为短的重复序列在精神分裂症患者中有过度表达，反之，也有许多家系研究没能证实SKCa通道蛋白基因（CAG）n长度与精神 …

Studies have revealed that KCNN4 is implicated in various physiological processes as well as promotes the malignant phenotypes of cancer cells. However, little is known about its associations with survival outcomes across varying cancer types.